Publications

2016

Regeneration of Liver Function Capacity After Partial Liver Resection is Impaired in Case of Postoperative Bile Leakage.

Pratschke J, Stockmann M, World J Surg. 2016 May 10. [Epub ahead of print]

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Effects of oxaliplatin-based chemotherapy on liver function-an analysis of impact and functional recovery using the LiMAx test.

Jara M, Bednarsch J, Malinowski M, Pratschke J, Stockmann M, Langenbecks Arch Surg 2016; 401(1):33-41.

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Monitoring of liver function in a 73-year old patient undergoing 'Associating Liver Partition and Portal vein ligation for Staged hepatectomy': case report applying the novel liver maximum function capacity test.

Oldhafer F, Ringe KI, Timrott K, Kleine M, Ramackers W, Cammann S, Jäger MD, Klempnauer J, Bektas H, Vondran FW, Patient Saf Surg. 2016 Jun 10;10:16. doi: 10.1186/s13037-016-0104-y.

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Application of the Liver Maximum Function Capacity Test in Acute Liver Failure: A Helpful Tool for Decision-Making in Liver Transplantation?  Case Rep Transplant.

Vondran FW, Schumacher C, Johanning K, Hartleben B, Knitsch W, Wiesner O, Jaeckel E, Manns MP, Klempnauer J, Bektas H, Lehner, F, 2016;2016:7074636. doi: 10.1155/2016/7074636. Epub 2016 May 4

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2015

Functional Liver Recovery After Bariatric Surgery-a Prospective Cohort Study with the LiMAx Test.

Alizai PH, Wendl J, Roeth AA, Klink CD, Luedde T, Steinhoff I, Neumann UP, Schmeding M, Ulmer F, Obes Surg 2015 Nov;25(11):247-53. PubMed PMID: 25869925.

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Noninvasive diagnosis of chemotherapy induced liver injury by LiMAx test – two case reports and a review of the literature.

Bednarsch J, Jara M, Lock JF, Malinowski M, Pratschke J, Stockmann M, BMC Res Notes. 2015 Mar 26;8(1):99. [Epub ahead of print] PubMed PMID: 25889706; PubMed Central PMCID: PMC4403679.

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13C Breath Tests Are Feasible in Patients With Extracorporeal Membrane Oxygenation Devices.

Bednarsch J, Menk M, Malinowski M, Weber-Carstens S, Pratschke J, Stockmann M, Artif Organs 2015.

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Nonalcoholic steatohepatits and liver steatosis modify partial hepatectomy recovery.

Hoppe S, von Loeffelholz C, Lock JF, Doecke S, Sinn BV, Rieger A, Malinowski M, Pfeiffer AF, Neuhaus P, Stockmann M, J Invest Surg 2015 Feb;28(1):24-31. doi:10.3109/08941939.2014.971206. Epub 2014 Nov 13. PubMed PMID: 25394215.

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Prognostic value of enzymatic liver function for the estimation of short-term survival of liver transplant candidates: a prospective study with the LiMAx test. 

Jara M, Malinowski M, Lüttgert K, Schott E, Neuhaus P, Stockmann M.Transpl, Int 2015 Jan;28(1):52-8. doi: 10.1111/tri.12441. Epub 2014 Sep 29. PubMed PMID: 25263095.

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Reductions in post-hepatectomy liver failure and related mortality after implementation of the LiMAx algorithm in preoperative work-up: a single-centre analysis of 1170 hepatectomies of one or more segments.

Jara M, Reese T, Malinowski M, Valle E, Seehofer D, Puhl G, Neuhaus P, Pratschke J, Stockmann M, HPB 2015 17(7):651-8.

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Sarcopenia, obesity and sarcopenic obesity: effects on liver function and volume in patients scheduled for major liver resection.

Lodewick TM, Roeth AA, Olde Damink SW, Alizai PH, van Dam RM, Gassler N, Schneider M, Dello SA, Schmeding M, Dejong CH, Neumann UP., J Cachexia   Sarcopenia Muscle. 2015 Jun;6(2):155-63

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Portal vein embolization with plug/coils improves hepatectomy outcome.

Malinowski M, Geisel D, Stary V, Denecke T, Seehofer D, Jara M, Baron A, Pratschke J, Gebauer B, Stockmann M, J Surg Res 2015 Mar;194(1):202-11. doi: 10.1016/j.jss.2014.10.028. Epub 2014 Oct 30. PubMed PMID: 25454977.

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Preliminary study on liver function changes after trisectionectomy with versus without prior portal vein embolization.

Malinowski M, Lock JF, Seehofer D, Gebauer B, Schulz A, Demirel L, Bednarsch J, Stary V, Neuhaus P, Stockmann M, Surg Today. 2015 Dec 31. [Epub ahead of print]

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Reliable assessment of liver function using LiMAx.

J Surg Res 2015 Jan;193(1):184-9. doi: 10.1016/j.jss.2014.07.041. Epub 2014 Jul 24. PubMed PMID: 25150081.

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2014

CT-Guided High-Dose-Rate Brachytherapy of Liver Tumours Does Not Impair Hepatic Function and Shows High Overall Safety and Favourable Survival Rates.

Brinkhaus G, Lock JF, Malinowski M, Denecke T, Neuhaus P, Hamm B, Gebauer B, Stockmann M., Ann Surg Oncol 2014 Dec;21(13):4284-92. doi: 10.1245/s10434-014-3835-y. Epub 2014 Jun 17. PubMed PMID: 24934583.

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Nonalcoholic steatohepatits and liver steatosis modify partial hepatectomy recovery. 

Hoppe S, von Loeffelholz C, Lock JF, Doecke S, Sinn BV, Rieger A, Malinowski M, Pfeiffer AF, Neuhaus P, Stockmann M., J Invest Surg 2015 Feb;28(1):24-31. doi:10.3109/08941939.2014.971206. Epub 2014 Nov 13. PubMed PMID: 25394215.

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Enhancing safety in liver surgery using a new diagnostic tool for evaluation of actual liver function capacity - The LiMAx test.

Jara M, Bednarsch J, Lock JF, Malinowski M, Schulz A, Seehofer D, Stockmann M., Dtsch Med Wochenschr 2014 Feb;139(8):387-91.

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Prognostic value of enzymatic liver function for the estimation of short-term survival of liver transplant candidates: a prospective study with the LiMAx test.

Jara M, Malinowski M, Lüttgert K, Schott E, Neuhaus P, Stockmann M., Transpl Int 2015 Jan;28(1):52-8. doi: 10.1111/tri.12441. Epub 2014 Sep 29. PubMed PMID:  25263095.

to publication

 

Portal vein embolization with plug/coils improves hepatectomy outcome.

Malinowski M, Geisel D, Stary V, Denecke T, Seehofer D, Jara M, Baron A, Pratschke J, Gebauer B, Stockmann M., J Surg Res 2015 Mar;194(1):202-11. doi: 10.1016/j.jss.2014.10.028. Epub 2014 Oct 30. PubMed PMID: 25454977.

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Enzymatic Liver Function Capacity Correlates with Disease Severity of Patients with Liver Cirrhosis: A Study with the LiMAx Test.

Malinowski M, Jara M, Lüttgert K, Orr J, Lock JF, Schott E, Stockmann M., Dig Dis Sci 2014 Dec;59(12):2983-91. doi: 10.1007/s10620-014-3250-z. Epub 2014 Jul 4. PubMed PMID: 24993690.

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Reliable assessment of liver function using LiMAx.

J Surg Res 2015 Jan;193(1):184-9. doi: 10.1016/j.jss.2014.07.041. Epub 2014 Jul 24. PubMed PMID: 25150081.

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Effect of delayed CNI-based immunosuppression with Advagraf® on liver function after MELD-based liver transplantation [IMUTECT].

Richter S, Polychronidis G, Gotthardt DN, Houben P, Giese T, Sander A, Dörr-Harim C, Diener MK, Schemmer P., BMC Surg 2014 Sep 1;14:64. doi: 10.1186/1471-2482-14-64. PubMed PMID: 25178675; PubMed Central PMCID: PMC4160448.

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2013

Assessment of Hepatic Detoxification Activity: Proposal of an Improved Variant of the 13C-Methacetin Breath Test.

Hermann-Georg Holzhütter, Johan Friso Lock, Pouria Taheri, Sascha Bulik, Andrean Goede, Martin Stockmann, PLoS One. 2013; 8(8): e70780

 

Nichtinvasive Diagnostik der Leberfunktion in der Transplantationsmedizin.

J.F.Lock, A.N. Kotobi, M. Malinowski, M. Jara, A. Schulz, P. Neuhaus und M. Stockmann, Verdauungskrankheiten, 2013 Jahrgang 31, Nr. 3/2013, S. 103–109

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Predicting the prognosis in acute liver failure: results from a retrospective pilot study using the LiMAx test.

Lock JF, Kotobi AN, Malinowski M, Schulz A, Jara M, Neuhaus P, Stockmann M,  Ann Hepatol. 2013 Jul-Aug;12(4):556-62.

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Predicting the prognosis in acute liver failure: results from a retrospective pilot study using the LiMAx test.

Lock JF, Kotobi AN, Malinowski M, Schulz A, Jara M, Neuhaus P, Stockmann M, Ann Hepatol. 2013 Jul-Aug;12(4):556-62.

 

Early diagnosis of sepsis-related hepatic dysfunction and its prognostic impact on survival: a prospective study with the LiMAx test.

Magnus F Kaffarnik, Johan F Lock, Hannah Vetter, Navid Ahmadi, Christian Lojewski, Maciej Malinowski, Peter Neuhaus and Martin Stockmann, Critical Care 2013, 17:R259

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A rapid and accurate new bedside test to assess maximal liver function: a case report.

Müller SA, Tarantino I, Corazza M, Pianka F, Fornaro J, Beutner U, Lüthi C, Schmied BM, Patient Safety in Surgery 2013, 7:11

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2012

Function and volume recovery after partial hepatectomy: influence of preoperative liver function, residual liver volume, and obesity.

Lock JF, Malinowski M, Seehofer D, Hoppe S, Röhl RI, Niehues SM, Neuhaus P, Stockmann M, Langenbecks Arch Surg. 2012 Jun 24.

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Accurate diagnosis and grading of cirrhosis using the new LiMAx test.

M. Stockmann, J.F. Lock, M. Malinowski, A. Scharfenberg, L. Morawietz, P. Neuhaus, Journal of Hepatology 2012 vol. 56 | S389–S548

 

2011

Initial liver graft function is a reliable predictor of tacrolimus trough levels during the first post-transplant week. 

Lock JF, Malinowski M, Schwabauer E, Martus P, Pratschke J, Seehofer D, Puhl G, Neuhaus P, Stockmann M, Clin Transplant 2011; 25:436-443

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Quantitative determination of metabolization dynamics by a real-time 13CO2 breath test.

Rubin, T., von Haimberger, T., Helmke, A., Heyne, K., J Breath Res. 2011, 5(2): 027102

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2010

Early Diagnosis of Primary Nonfunction and Indication for Reoperation After Liver Transplantation.

Lock JF, Schwabauer E, Martus P, Videv N, Pratschke J, Malinowski M, Neuhaus P, Stockmann M, Liver Transpl 2010; 16:172-180

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How to define initial poor graft function after liver transplantation? - a new functional definition by the LiMAx test. 

Stockmann M, Lock JF, Malinowski M, et al., Transpl Int 2010; 23(10):1023-32

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The LiMAx test: a new liver function test for predicting postoperative outcome in liver surgery.

Stockmann M, Lock JF, Malinowski M, Niehues SM, Seehofer D, Neuhaus P., HPB 2010; 12:139-46

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2009

The costs of postoperative liver failure and the economic impact of liver function capacity after extended liver resection – a single center experience.

Lock JF, Reinhold T, Malinowski M, Pratschke J, Neuhaus P, Stockmann M, Langenbecks Arch Surg 2009; 394:1047-56

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Interpretation of Non-Invasive Breath Tests Using 13C-labeled Substrates – A Preliminary Report With 13C-Methacetin.

Lock JF, Taheri P, Bauer S, Holzhütter HG, Malinowski M, Neuhaus P, Stockmann M, Eur J Med Res 2009; 14:547-50

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Prediction of postoperative outcome after hepatectomy with a new bedside test for maximal liver function capacity.

Stockmann M, Lock JF, Riecke B, Heyne K, Martus P, Fricke M, Lehmann S, et al., Ann Surg, 2009; 250:119-25

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